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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T10861 | Collagen proline hydroxylase inhibitor-1 | Others | |
Collagen proline hydroxylase inhibitor-1 exhibits antifibroproliferative activity. | |||
TP1643 | Alpha 1(I) Collagen (614-639), human | ||
This is a peptide inhibitor of collagen fibrillar matrix assembly. | |||
T60303 | Collagen-IN-1 | ||
Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative exhibiting selective inhibition of collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Coll... | |||
T16886 | Sinefungin | Adenosyl-Ornithine,A-9145,Antibiotic 32232RP | Others , Histone Methyltransferase , Antibiotic , Antifungal |
Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7/9 inhibitor and ameliorates r... | |||
T4283 | SRI-011381 | TGF-beta/Smad | |
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease. | |||
TP2452 | Collagen type IV alpha1 (531-543) | Hep III peptide,Gefyfdlrlkgdk | |
Collagen type IV alpha1 (531-543) is a protein that in humans is encoded by the COL4A1 gene on chromosome 13. It is ubiquitously expressed in many tissues and cell types. COL4A1 is a subunit of type IV collagen and plays... | |||
T5129 | SRI-011381 hydrochloride | SRI-011381 hydrochloride [1629138-41-5(free base)] | TGF-beta/Smad |
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease. | |||
T1606 | Fasudil | HA-1077,AT877 | ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy |
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK. | |||
T3060 | Fasudil hydrochloride | Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877 | ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy |
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively. | |||
T38369 | CAY10678 | Prostaglandin Receptor , PD-1/PD-L1 | |
CAY10678 is an mPGES-1 inhibitor that inhibits PD-1.CAY10678 reduces collagen deposition and T-cell depletion, and may be used to study melanoma.CASHIPS | |||
T2386 | Pirfenidone | S-7701,AMR-69,S-7701,AMR69 | CCR , TGF-beta/Smad |
Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tum... | |||
T24816 | SP-100030 | SP100030,SP 100030 | NF-κB |
SP-100030 is a dual inhibitor of NF-κB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and ... | |||
T38294 | 4-Deoxypyridoxine hydrochloride | S1P Receptor | |
4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. 4-DPD inhib... | |||
T27170 | Diethyl pyimDC | ||
Diethyl pyimDC is an inhibitor of human collagen prolyl 4-hydroxylase 1 (CP4H1). | |||
T26596 | Allylpyrocatechol | ||
Allylpyrocatechol is an antioxidant. Allylpyrocatechol attenuates collagen-induced arthritis via attenuation of oxidative stress secondary to modulation of the MAPK, JAK/STAT, and Nrf2/HO-1 pathways. | |||
T80025 | Bovine Type II Collagen | Collagen, Type II, Immunization Grade | |
Type II collagen is a protein that demonstrates considerable effectiveness in alleviating pain and inflammation associated with collagen-induced arthritis in mice, with notable application in the treatment of osteoarthri... | |||
T61697 | GPVI antagonist 1 | ||
GPVI antagonist 1 (compound 5) functions as an antagonist for the glycoprotein VI (GPVI) platelet receptor. It effectively inhibits collagen-induced platelet aggregation, demonstrating an IC50 value of 25.3 μM [1]. | |||
T78030 | GRGESP | ||
GRGESP is a collagen gel contraction inhibitor that impedes the spreading of human fibroblasts within collagen gels and significantly reduces gel contraction, thus serving as a valuable agent for research in connective t... | |||
T35725 | 4-hydroxy Valsartan | ||
4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood. | |||
T74402 | FAP-PI3KI1 | ||
FAP-PI3KI1, a fibroblast-activated protein (FAP)-targeted PI3K inhibitor, selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells. It effectively inhibits collagen synthesis and reduces collage... | |||
T82467 | Endotrophin (Mus musculus) | ||
Endotrophin (Mus musculus), a cleavage product of collagen 6 (Col6), induces upregulation of profibrotic and proinflammatory genes [1]. | |||
TP2354 | Tetrapeptide-11 | Pro-pro-tyr-leu | |
Tetrapeptide-11 is the reaction product of Acetic Acid and tetrapeptide-11, containing leucine, proline, and tyrosine residues. It boosts cell growth, Syndecan-1, and Collagen XVII synthesis. Tetrapeptide-11 has a face a... | |||
T36929 | Pal-KTTKS (acetate) | ||
Pal-KTTKS is a lipidated pentapeptide consisting of a fragment of the type I collagen C-terminal propeptide conjugated to palmitic acid .1 It increases collagen production in human corneal and dermal fibroblasts when use... | |||
TP2186 | PalMitoyl Tripeptide-1 | Others | |
PalMitoyl Tripeptide-1 affects the synthesis of collagen, fibronectin and hyaluronic acid in human skin fibroblasts and can be used to prepare anti-aging cosmetics. | |||
T61811 | GPVI antagonist 3 | ||
GPVI antagonist 3 (Compound 2) is a potential antagonist that shows promising antiplatelet activity by selectively inhibiting the interaction between the Glycoprotein VI (GPVI) receptor and its ligands. It demonstrates p... | |||
T36930 | Palmitoyl Tetrapeptide-7 (acetate) | ||
Palmitoyl tetrapeptide-7 is a cosmeceutical peptide that stimulates type I collagen, fibronectin, and hyaluronic acid production in skin.1Formulations containing palmitoyl tetrapeptide-7 have been used in the treatment o... | |||
T80746 | YYRADDA | ||
YYRADDA, a polypeptide, enhances collagen production within the skin's extracellular matrix, thus improving skin appearance and aiding the repair of damaged skin [1]. | |||
T60557 | TRAP-6-IN-1 | ||
TRAP-6-IN-1 (Compound 8) is a dual inhibitor of collagen and TRAP-6 with IC 50 values of 17.12 μM and 11.88 μM, respectively. TRAP-6-IN-1 non-competitively inhibits agonist-induced platelet aggregation[1]. | |||
T81005 | Tetrapeptide-4 | ||
Tetrapeptide-4 is a peptide commonly incorporated into skincare formulations for its anti-aging benefits, which include diminishing wrinkles and fortifying collagen, elastin, and fibronectin [1]. | |||
T82780 | Caprooyl-tetrapeptide-3 acetate | ||
Caprooyl-tetrapeptide-3 acetate, employed for diminishing fine lines and wrinkles, enhances collagen VII and laminin-5 expression in corticoid-induced skin aging models [1]. | |||
TP2186L1 | PalMitoyl Tripeptide-1 hydrochloride | PalMitoyl Tripeptide-1 hydrochloride(147732-56-7 Free base) | Others |
PalMitoyl Tripeptide-1 hydrochloride (PalMitoyl Tripeptide-1 hydrochloride (147732-56-7 Free base)) has effects on the synthesis of collagen, fibronectin and hyaluronic acid in human skin fibroblasts, and can be used in ... | |||
T73770 | Galactosylhydroxylysine hydrochloride | ||
Galactosylhydroxylysine hydrochloride, a bone collagen component generated through hydroxylysine's post-translational glycosylation, is liberated during bone resorption. Its levels increase in cases of metabolic bone los... | |||
T11729 | JTE-952 | Histamine Receptor | |
JTE-952 is a oral, potent active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , resp... | |||
T61586 | TGFβ-IN-2 | ||
TGFβ-IN-2 (Compound 9d) effectively inhibits the accumulation of total collagen induced by TGF-β in NRK-49F cells, with an IC 50 value of 4.31 μM. It also suppresses the in vitro protein expression of COL1A1, α-SMA, and ... | |||
T41079 | MMP13-IN-2 | MMP13-IN-2 | |
MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over... | |||
T80859 | Vitronectin | ||
Vitronectin, a multifunctional glycoprotein found in blood and the extracellular matrix, interacts with glycosaminoglycans, collagen, plasminogen, and the urokinase-receptor, in addition to stabilizing the inhibitory con... | |||
T62250 | GPVI antagonist 2 | ||
GPVI antagonist 2 (Compound 1) is a potential Glycoprotein VI (GPVI) antagonist, able to act on collagen (IC50: 0.35 μM), CRP (IC50: 0.80 μM), convulxin (IC50: 195.2 μM), thrombin (IC50. 81.38 μM). GPVI antagonist 2 is a... | |||
T78219 | Obtustatin triacetate | Integrin | |
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of the integrin α1β1's adhesion to type IV collagen. This compound hol... | |||
T79260 | MCI | Reactive Oxygen Species | |
MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation through macrophage reprogramming by enhancing ROS scavenging a... | |||
T74632 | TP0556351 | MMP | |
TP0556351, a potent and selective inhibitor of matrix metalloproteinase-2 (MMP2), exhibits significant efficacy with an IC50 of 0.2 nM and demonstrates the capability to decrease collagen accumulation in a Bleomycin-indu... | |||
T78038 | H-Pro-Gly-Pro-OH | ||
H-Pro-Gly-Pro-OH, a collagen-derived matrikine, traditionally acts as a neutrophil chemoattractant, guiding these cells to target locations to orchestrate localized repair responses. Additionally, this compound initiates... | |||
T69671 | SR1903 TFA | ||
SR-1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR). It is an inverse agonist of RORγ and an agonist of LXR. It also binds to peroxisome proliferator-activated rec... | |||
T36101 | Psychotridine | ||
Psychotridine is an alkaloid that has been found inP. forsterianaand has diverse biological activities.1,2,3It inhibits ADP-, collagen-, or thrombin-induced aggregation of washed isolated human platelets with IC50values ... | |||
T60854 | ENMD-1068 hydrochloride | ||
ENMD-1068 hydrochloride, a selective protease-activated receptor 2 (PAR2) antagonist, inhibits TGF-β1/Smad signaling, thereby reducing hepatic stellate cell activation and collagen expression. It also suppresses the prol... | |||
T81592 | Osteostatin | PTHrP (107–111) | |
Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presenting with bone defects and exhibits efficacy in mitigating bone e... | |||
T35695 | Oleic Acid-13C | ||
Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been fo... | |||
T35638 | SR 1903 | ||
SR 1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR).1 It is an inverse agonist of RORγ (IC50 = ~100 nM in a cell-based reporter assay) and an agonist of LXR. It al... | |||
T74142 | Angiotensin II human TFA | ||
Angiotensin II human TFA, a potent vasoconstrictor within the renin/angiotensin system, plays a pivotal role in human blood pressure regulation primarily through interactions with the G-protein-coupled receptors Angioten... | |||
T36486 | Benpyrine | ||
Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the poten... | |||
T36717 | RWJ-56110 dihydrochloride | ||
RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T6856 | Halofuginone | Tempostatin,empostatin,RU-19110 | Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal. | |||
T3524 | Halofuginone hydrobromide | Tempostatin,RU-19110 (hydrobromide),Stenorol | Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce... | |||
T3S1944 | Darutoside | Darutin | Others |
1. Darutoside (Darutin) can as an appropriate treatment for wounds. 2. Darutoside can improve skin elasticity, surface appearance and stretch mark removal, through soothing the skin, decreasing inflammation, restoring co... | |||
TN6975 | Cirsiumaldehyde | 5,5’-oxydimethylenebis(2-furfural) | Platelet aggregation |
Cirsiumaldehyde is a compound isolated from the mature fruits of Lobelia chinensis, Cornus officinalis, and the fruits of Hippophae rhamnoides.Cirsiumaldehyde in the presence of collagen inhibited U46619-induced (1~5 uM)... | |||
T2769 | 3-Aminopropionitrile fumarate (2:1) | Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate | Others |
3-Aminopropionitrile fumarate (2:1) (β-Aminopropionitrile fumarate) is an organic compound and antirheumatic agent used in veterinary medicine. | |||
T4S0498 | Glaucocalyxin A | Wangzaozin B,Leukamenin F | Apoptosis , Akt , Caspase , PI3K |
1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi... | |||
T72798 | Ganodermaones B | ||
Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression . | |||
T79983 | Flaccidoside II | Apoptosis | |
Flaccidoside II, an active triterpenoid saponin from Anemone flaccida rhizome, both inhibits proliferation and induces apoptosis in Malignant Peripheral Nerve Sheath Tumors (MPNSTs) cell lines and ameliorates collagen-in... | |||
TN4664 | Norarmepavine | Others | |
N-norarmepavine shows significant cytotoxic activities against HL-60 carcinoma cell line with inhibitory ratios of 51.43% at concentration of 1 x 10(-5) M. Norarmepavine shows inhibition against Trypanosoma cruzi. D-(+)-... | |||
T38330 | Collinin | ||
Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Col... | |||
T35624 | Ajoene | ||
Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-01395 | CTHRC1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CTHRC1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.5 kDa and the accession number is Q96CG8-1. | |||
TMPY-05556 | Adiponectin Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Adiponectin Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26 kDa and the accession number is A8K660. | |||
TMPY-02848 | Adiponectin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Adiponectin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q15848. | |||
TMPJ-00948 | Endostatin Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and/or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑termi... | |||
TMPJ-00804 | COL3A1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Collagen alpha-1(III) chain(Col3a1) is a secreted protein and belongs to the fibrillar collagen family.It contains 1 fibrillar collagen NC1 domain and 1 VWFC domain. Collagen alpha-1(III) chain is a fibrillar collagen th... | |||
TMPJ-00921 | COL8A1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the basement membrane of the corneal endo... | |||
TMPJ-01281 | COL21A1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one TSP N-terminal (TSPN) do... | |||
TMPY-06775 | CTHRC1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CTHRC1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.8 kDa and the accession number is NP_612464.1. | |||
TMPY-06826 | CTHRC1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
CTHRC1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 26.33 kDa and the accession number is NP_612464.1. | |||
TMPY-04288 | CTHRC1 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
CTHRC1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is NP_001258229.1. | |||
TMPY-01860 | Collagen II/COL2A1 Protein, Human, Recombinant (aa 1242-1487, His) | Human | HEK293 Cells |
COL2A1 is the alpha-1 chain of type II collagen which is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this protein are associated with achondrogenesis, chondrodysplasia, early o... | |||
TMPY-04015 | COL9A1 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3. | |||
TMPH-01113 | COL8A1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
COL8A1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-01117 | COL18A1 Protein, Human, Recombinant (GST) | Human | E. coli |
COL18A1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 46.3 kDa and the accession number is P39060. | |||
TMPH-01111 | COL4A1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
COL4A1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-03960 | COL9A1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3. | |||
TMPY-02596 | GLT25D2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Glycosyl transferase 25 domain 2 (GLT25D2) is a glucosyltransferase enzyme expressed only at low levels in the nervous system. Glycosyltransferases are enzymes that act as a catalyst for the transfer of a monosaccharide ... | |||
TMPH-01118 | COL18A1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
COL18A1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 21.3 kDa and the accession number is P39060. | |||
TMPY-06795 | CTHRC1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CTHRC1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.53 kDa and the accession number is Q9D1D6. | |||
TMPH-02588 | COL12A1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix. | |||
TMPH-01112 | COL4A1 Protein, Human, Recombinant (GST) | Human | E. coli |
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Arresten, comprising the C-termina... | |||
TMPH-01115 | COL15A1 Protein, Human, Recombinant (His) | Human | E. coli |
COL15A1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-01114 | COL12A1 Protein, Human, Recombinant (His) | Human | E. coli |
COL12A1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02593 | CTHRC1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
May act as a negative regulator of collagen matrix deposition. | |||
TMPH-02589 | COL26A1 Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
N/A. COL26A1 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 47.7 kDa and the accession number is Q91VF6. | |||
TMPH-01123 | CTHRC1 Protein, Human, Recombinant (aa 31-243, hFc) | Human | HEK293 Cells |
May act as a negative regulator of collagen matrix deposition. CTHRC1 Protein, Human, Recombinant (aa 31-243, hFc) is expressed in HEK293 mammalian cells with C-hFC tag. The predicted molecular weight is 52 kDa and the a... | |||
TMPH-02592 | CTHRC1 Protein, Mouse, Recombinant (aa 33-245, His) | Mouse | HEK293 Cells |
May act as a negative regulator of collagen matrix deposition. | |||
TMPH-01116 | COL17A1 Protein, Human, Recombinant (His) | Human | E. coli |
May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.; The 120 kDa linear IgA disease antigen is an anchoring filament component involved in derm... | |||
TMPH-00219 | Adiponectin Protein, Bovine, Recombinant (His) | Bovine | P. pastoris (Yeast) |
Adiponectin Protein, Bovine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is Q3Y5Z3. | |||
TMPH-00350 | Adiponectin Protein, Feline, Recombinant | Feline | E. coli |
Adiponectin Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 24.9 kDa and the accession number is A4PB30. | |||
TMPJ-00995 | Serpin H1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is th... | |||
TMPY-02953 | TEM8/ANTXR1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are ser... | |||
TMPJ-01172 | IL-17 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque... | |||
TMPY-00203 | LOXL2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 ... | |||
TMPH-02402 | Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His) | Legionella pneumophila | E. coli |
Cleaves collagen, gelatin, casein, alpha-1-antitrypsin, and bovine insulin. May play a role in the pathogenesis of legionnaires disease. | |||
TMPJ-00605 | GPVI Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregat... | |||
TMPY-04671 | MCP-5 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impa... | |||
TMPK-01389 | Fibronectin Protein, Human, Recombinant (aa 32-345, His) | Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells ... | |||
TMPK-01390 | Fibronectin Protein, Human, Recombinant (aa 32-602, His) | Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells ... | |||
TMPK-01190 | GPVI Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycopro... | |||
TMPH-02813 | Nidogen-1 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions. Nidogen-1 Prot... | |||
TMPY-01826 | Relaxin 1/RLN1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Relaxin-1, also known as Prorelaxin H1 and RLN1, is a secreted protein that belongs to the insulin family. It is a peptide hormone that was first described in 1926 by Frederick Hisaw. Since its discovery as a reproductiv... | |||
TMPH-02513 | TEM8/ANTXR1 Protein, Mouse, Recombinant (His & Myc) | Mouse | HEK293 Cells |
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskel... | |||
TMPH-02512 | TEM8/ANTXR1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskel... | |||
TMPJ-01444 | IL-17A Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it ... | |||
TMPJ-00566 | MFAP4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Microfibril-associated glycoprotein 4(MFAP4) is a secreted protein and contains 1 fibrinogen C-terminal domain, similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collag... | |||
TMPY-03272 | COL4A3 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix s... | |||
TMPJ-01333 | TEM8/ANTXR1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothel... | |||
TMPJ-00447 | MMP-3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue rem... | |||
TMPJ-00442 | Otolin-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Otolin (OTOL1), also known as C1qTNF15, is an approximately 65 kDa protein found in the otoconial membrane lining the cochlea and vestibular labyrinth of the inner ear. Collagen-like protein specifically expressed in the... | |||
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